Results 101 to 110 of about 529,278 (267)

Design and Experimental Validation of a Line-Laser Autofocusing System With Extended Working Range

open access: yesIEEE Photonics Journal
Autofocus (AF) technology plays a critical role in applications such as microscopic measurement, 3D visual scanning, and semiconductor defect inspection.
Xiaoxiao Wei   +4 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Cost-effective and Sensitive Anthocyanin-Based Purple Cabbage (Brassica Oleracea var. Capitata L) Extract Biosensor for Diagnostic Spoilage Fish Product

open access: yesJournal of Studies in Science and Engineering
Purple cabbage (Brassica oleracea var. capitata f. rubra) contains anthocyanins that exhibit pH-dependent colour changes and can function as visual indicators of food spoilage through their response to volatile basic compounds.
Lusiani Dewi Assaat   +2 more
doaj   +1 more source

Novel photo-detectors and photo-detector systems

open access: yesNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2009
7 pages, 6 figures, prepared for Position Sensitive Detectors ...
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Gepta-EX: a multi-channel germanium detector for X-ray absorption fine structure

open access: yesJournal of Synchrotron Radiation
Fluorescence-mode X-ray absorption spectroscopy (XAS) at high photon energies requires detectors with high stopping power and excellent energy resolution to measure weak element-specific signals.
Abdul K. Rumaiz   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Thermalization of Mesh Reinforced Ultra-Thin Al-Coated Plastic Films: A Parametric Study Applied to the Athena X-IFU Instrument

open access: yesSensors
The X-ray Integral Field Unit (X-IFU) is one of the two focal plane detectors of Athena, a large-class high energy astrophysics space mission approved by ESA in the Cosmic Vision 2015–2025 Science Program.
Nicola Montinaro   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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