Results 161 to 170 of about 1,035,998 (303)

Integrated high-rate transition radiation detector and tracking chamber for the LHC

, 1990
The development of an integrated transition radiation detector (TRD) and charged-particle tracker for use in an LHC detector is proposed. The purpose of such a detector is to identify electrons efficiently, while rejecting the potentially very large ...
CERN. Geneva. Detector Research and Development Committee
core  

It Is All About Energy-the Changing Role of X-ray Photons in Photon-counting Detector Computed Tomography: What the Radiologist Needs to Know About kV and keV. [PDF]

Invest Radiol
Hoeijmakers EJI, Martens B, Wildberger JE, Flohr TG, Jeukens CRLPN.   +4 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Characterization of a Resistively Multiplexed SiPM Readout for Position-Sensitive Scintillating Fibre Radiation Detectors. [PDF]

Sensors (Basel)
Žagar K, Košir G, Vencelj M, Lovšin E, Mulder T, Gerl J, Huang H, Li GS, Vesić J, FIMP Collaboration.   +9 more
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Advancements in the Application of CVD Diamond Detectors for Space Radiation Monitoring. [PDF]

Nanomaterials (Basel)
Meng Q, Shen G, Yang Z, Hou D, Zhang H, Quan Z, Sun Y.   +6 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Differential pathlength factor model for near-infrared diffuse optical imaging. [PDF]

Biomed Opt Express
Niknam K, Paul MB, Das M.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Physiology-Informed Blink Artefact Detection from Bilateral Frontal EEG Under Asymmetric Interference. [PDF]

Bioengineering (Basel)
Zhang W, Li M, Zhang Y, Cao J, Shen F, Liu X, Chen C, Li Y.   +7 more
europepmc   +1 more source