Results 191 to 200 of about 2,087,074 (350)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

AN AUTOMATIC FLAW DETECTOR FOR ALUMINUM CANS

, 1956
James D. Ross
openalex   +2 more sources

Discussion: “Combustion Studies Using the Golay Photothermal Detector With an Infrared Monochromator” (Agnew, J. T., 1949, Trans. ASME, 71, pp. 107–114) [PDF]

, 1949
F. B. Downing
openalex   +1 more source

User evaluation of detector performance in clinical photon-counting and energy-integrating CT scanners using DICOM images. [PDF]

Med Phys
Li K, Liu X, Jacobsen MC, Rong J, Jensen CT, Tamm EP, Dong F.   +6 more
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Rapid Method for Determination of Low Concentrations of Ammonia and Carbon Dioxide in Air by means of Detector Tubes

, 1958
Yoshitaka Kobayashi, Akio Matsumoto, Takeshi Yamada   +2 more
openalex   +2 more sources

A NONBOND DETECTOR FOR HOLLOW SLUGS [PDF]

, 1956
Jonathan Ross, R.W. Leep
openalex   +1 more source

The CRAB facility at the TU Wien TRIGA reactor: status and related physics program. [PDF]

Eur Phys J C Part Fields
Abele H, Ajello P, Armatol A, Arnold B, Billard J, Bossio E, Burkhart J, Cappella F, Casali N, Cerulli R, Colas J, Crocombette JP, Del Castello G, Del Gallo Roccagiovine M, Dorer S, Doutre C, Erhart A, Fichtinger S, Friedl M, Garin P, Gergen R, Goupy C, Hainz D, Hauff D, Jericha E, Kaznacheeva M, Kluck H, Lasserre T, Lhuillier D, Litaize O, de Marcillac P, Marnieros S, Martin R, Namuth E, Ortmann T, Poda DV, Peters L, Reindl F, Reindl W, Rodari F, Rothe J, Schermer N, Schieck J, Schönert S, Schwertner C, Soum-Sidikov G, Strauss R, Thalmeier R, Thulliez L, Trunner C, Vignati M, Vivier M, Wasser P, Wex A.   +53 more
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Partial orientation retrieval of proteins from X-ray free-electron-laser induced explosions for single particle imaging. [PDF]

Sci Rep
André T, Bellisario A, De Santis E, Tîmneanu N, Caleman C.   +4 more
europepmc   +1 more source