Results 241 to 250 of about 2,087,074 (350)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Wide-band detector for micro-microampere low-energy electron currents [PDF]

, 1960
T. E. Everhart, R. Thornley
openalex   +1 more source

Evaluating dosimetric parameters with a plastic scintillator for megavoltage photon beam quality assurance. [PDF]

J Appl Clin Med Phys
Penoncello G, Jones BL, Dunkerley DAP, Mahl A, Miften M, Altunbas C, Wang CC, Robertson DG.   +7 more
europepmc   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Light transport in the human spine for optical bone density assessment: Monte Carlo modeling and validation. [PDF]

Biomed Opt Express
Wang F, Su H, Yang C, Li T.
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

A Rapid Method for the Determination of Dimethyl Ether in Methyl Chloride by Detector Tubes

, 1955
Yoshitaka Kobayashi
openalex   +2 more sources

Three-dimensional reconstruction of a small piece of Ce-doped lithium glass scintillator of an optical fiber-based neutron detector using microcomputed tomography technique. [PDF]

J Radiat Res
Ishikawa A, Segawa M, Toh Y, Watanabe K, Masuda A, Matsumoto T, Yamazaki A, Yoshihashi S, Uritani A, Harano H.   +9 more
europepmc   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Rapid Method for Determination of Vinyl Chloride Vapor in Ammonia by Means of Detector Tubes

, 1958
Yoshitaka Kobayashi
openalex   +2 more sources