Results 271 to 280 of about 2,140,853 (301)

The Amerigo Vespucci as a traveling laboratory for studying the cosmic-ray fluxes at sea level. [PDF]

Sci Rep
Cerasole D, Cuna F, De Palma G, Di Tria R, Di Venere L, Gargano F, Giliberti M, Licciulli F, Liguori A, Loizzo P, Loparco F, Lorusso L, Mazziotta MN, Panzarini G, Pillera R, Serini D.   +15 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Performance evaluation of the ACTIVE 7 MAX benchtop preclinical PET scanner in accordance with the NEMA NU 4-2008 standard. [PDF]

EJNMMI Phys
Wang H, Wang K, Yuan Z, Li C, Liao R, Hou Y, Hua J, Tang Y, Ruan Q, Han D, Jiang J.   +10 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

International database of reference gamma spectra for nuclear safeguards applications. [PDF]

Sci Data
Dipti, Marian L, Hill C, Koning A, Bland JJ, Schwartz SR, Dreyer J, Vo DT, Carbonaro J, Berlizov A.   +9 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Oriented object detection in remote sensing images based on angle quality estimation. [PDF]

Sci Rep
Li C.
europepmc   +1 more source

3D Imaging of Proton FLASH Radiation Using a Multi-Detector Small Animal PET System. [PDF]

Tomography
Li W, Zhong Y, Lai Y, Yin L, Sforza D, Miles D, Li H, Jia X.   +7 more
europepmc   +1 more source

Helium range viability for online range probing in mixed carbon-helium beams. [PDF]

Med Phys
Hardt JJ, Pryanichnikov AA, Jäkel O, Seco J, Wahl N.   +4 more
europepmc   +1 more source

Analysis of the Influence of Farmer Behavior on Heavy Metal Pollution in Farmland Soil: A Case Study of Shouyang County, Shanxi Province. [PDF]

Toxics
Han JX, Liang YJ, Ban FM.
europepmc   +1 more source