Results 101 to 110 of about 5,097,408 (330)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Loss-tolerant measurement-device-independent quantum random number generation

New Journal of Physics, 2015
Quantum random number generators (QRNGs) output genuine random numbers based upon the uncertainty principle. A QRNG contains two parts in general—a randomness source and a readout detector.
Zhu Cao, Hongyi Zhou, Xiongfeng Ma
doaj   +1 more source

Plasmonic-Layered InAs/InGaAs Quantum-Dots-in-a-Well Pixel Detector for Spectral-Shaping and Photocurrent Enhancement

Nanomaterials, 2020
The algorithmic spectrometry as an alternative to traditional approaches has the potential to become the next generation of infrared (IR) spectral sensing technology, which is free of physical optical filters, and only a very small number of data are ...
Jehwan Hwang, Zahyun Ku, Jiyeon Jeon, Yeongho Kim, Jun Oh Kim, Deok-Kee Kim, Augustine Urbas, Eun Kyu Kim, Sang Jun Lee   +8 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The XENON program for dark matter direct detection

Nuclear Physics B
The XENON family of experiments have been at the forefront of direct dark matter searches for weak-scale dark matter for more than fifteen years. In this time, the program has scaled from a few-kilogram pathfinder detector to the current XENONnT holding ...
Elena Aprile
doaj   +1 more source

Probing seed black holes using future gravitational-wave detectors

, 2009
Identifying the properties of the first generation of seeds of massive black holes is key to understanding the merger history and growth of galaxies. Mergers between ~100 solar mass seed black holes generate gravitational waves in the 0.1-10Hz band that ...
Acernese F, Ajith P, Alberto Sesana, Alberto Vecchio, Alvarez M A Wise J H Abel T, Arun K G, Bender P, Bender P L Armitage P J Begelman M C Pema R, Freise A, Fritschel P, Grote H, Hild S Chelkowski S Freise A, Hild S Chelkowski S Freise A Franc J Morgado N Flaminio R DeSalvo R, Hopkins P, Ilya Mandel, Jonathan R Gair, Kawamura S, Madau P, Milosavljevic M, Phinney E S, Plowman J E Jacobs D C Hellings R W Larson S L Tsuruta S, Sesana A, Sesana A, Sigg D, Spergel D N, van der Sluys M Mandel I Raymond V Kalogera V Roever C Christensen N, Volonteri M, Wyithe J S B   +27 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Future neutrino physics with Hyper-Kamiokande [PDF]

EPJ Web of Conferences
Hyper-Kamiokande, the next-generation neutrino observatory in Japan, evolves from its predecessors, Kamiokande, Super-Kamiokande and T2K, with a significant upgrade to a 258-kton water Cherenkov detector equipped with 20,000 PMTs.
Jesús-Valls César
doaj   +1 more source