Results 191 to 200 of about 296,935 (264)

Characterization of a novel plastic scintillation detector for in vivo electron dosimetry. [PDF]

J Appl Clin Med Phys
Bauer CJ, Schneider F, Göbel ID, Oppitz H, Giordano FA, Fleckenstein J.   +5 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

3D Reactive Oxygen Species Dosimetry in Pleural Photodynamic Therapy: Integration of Macroscopic Kinetic Modeling and Deformable Registration. [PDF]

Antioxidants (Basel)
Sun H, Kim MM, Dimofte A, Singhal S, Cengel KA, Zhu TC.   +5 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

High-Speed Volumetric Dual-Mode Ultrasound and Photoacoustic Tomography With a Single-Element Detector. [PDF]

IEEE Trans Med Imaging
Basumatary J, Aborahama Y, Zhang Y, Zhang Y, Zeng Y, Liu CZ, Zhou Q, Wang LV.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Exploration of Copper Halide Linear-Array Detector Prototype for Security Checks. [PDF]

Small
Zhou Y, He T, Shao W, Wu W, Yuan P, Xie H, Bakr OM, Mohammed OF.   +7 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Comparing energy-integrating detector and photon-counting detector-based breast cone beam CTs for microcalcification detection via Monte Carlo simulation. [PDF]

Phys Med Biol
Ollah Ezzati A, Hu X, Qi M, Lai Y, Zhong Y, Yang K, Jia X.   +6 more
europepmc   +1 more source