Results 71 to 80 of about 378,573 (266)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
First test of cold edgeless silicon microstrip detectors
Silicon microstrip detectors will provide the forward tracking in the TOTEM experiment at the LHC. To allow efficient tracking closest to the beam ( approximately equals 1 mm) these detectors should be sensitive up to their physical edge (i.e. edgeless).
B. Perea Solano +31 more
core +1 more source
Recent results from beam tests of large area silicon drift detectors [PDF]
Silicon drift detectors with an active area of 7.0 × 7.5 cm2 will equip the two middle layers of the Inner Tracking System of the ALICE experiment. The performance of several prototypes was studied during beam tests carried out at the CERN SPS facility ...
Wheadon, R +33 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Fabrication of PIN diode detectors on thinned silicon wafers
Thin substrates are one of the possible choices to provide radiation hard detectors for future high-energy physics experiments. Among the advantages of thin detectors are the low full depletion voltage, even after high particle fluences, the improvement ...
Guarnieri, Vittorio +6 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Gaseous Detectors: Charged Particle Detectors - Particle Detectors and Detector Systems
Gaseous Detectors in 'Charged Particle Detectors - Particle Detectors and Detector Systems', part of 'Landolt-Börnstein - Group I Elementary Particles, Nuclei and Atoms: Numerical Data and Functional Relationships in Science and Technology, Volume 21B1 ...
Hilke, H J, H. J. Hilke
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Selective gas chromatographic detectors /
This book gives a comprehensive, up-to-date review of all selective detectors used in combination with gas chromatography. For each detector, the historical background, design and principle are described, and the working parameters affecting the detector
Dressler, M.
core

