Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh +2 more
wiley +1 more source
A Novel Cobalt-Activated Halotolerant α-Amylase with High Specific Activity from <i>Priestia</i> sp. W243 in Kuwait Sabkha for Biotechnological Applications. [PDF]
Alagarsamy S +6 more
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Production of Novel Thermostable Esterases from <i>Thermus thermophilus</i> Strain ET-1 in <i>Escherichia coli</i> and <i>Thermus thermophilus</i> HB27 Using the Bifunctional Expression System pTGT-1 and Characterization of the Recombinant Enzymes. [PDF]
Valenzuela B +6 more
europepmc +1 more source
Abstract Background Studies show increased use of home enteral nutrition (HEN) owing to its benefits. However, knowledge about the sanitary risks of handling home‐prepared formulas remains limited despite their high contamination rates. This study aimed to assess the sanitary risks in the handling of home‐prepared enteral formulations by analyzing ...
Marcelly Caroline Pires Fernandes +6 more
wiley +1 more source
Authors' reply: Reuse of single-use Kahook Dual Blade: Safety and ethics. [PDF]
Sethi SS, Sethi A.
europepmc +1 more source
PTQ10‐based organic photodetectors for visible light detection and their tolerance to impurities
PTQ10‐based organic photodetectors were found to be very sensitive to the presence of Pd(PPh3)4 catalyst traces, impacting the transport properties and light detection capacities. Abstract PTQ10 donor polymer has attracted a lot of interest in organic optoelectronics, particularly in the field of organic photovoltaics, owing to its ease of synthesis ...
Chloé Dindault +9 more
wiley +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Comparative evaluation of the biocompatibility and antibacterial efficacy of various toothpaste formulations. [PDF]
Aşık A +8 more
europepmc +1 more source
Probiotic-Based Cleaning Solutions: From Research Hypothesis to Infection Control Applications. [PDF]
Falagas ME +5 more
europepmc +1 more source

