Results 41 to 50 of about 150,348 (305)

Milk Adulterants: Serious Impact on Human Health

open access: yesJournal of Medical Evidence
Milk has been an indispensable part of our diet because of its rich content of vital nutrients. The demand and supply gap in milk production along with its perishable nature have resulted in the increased menace of milk adulteration.
Madhu Choudhary, Nitin Sharma
doaj   +1 more source

Differential characteristics of purified hepatic triglyceride lipase and lipoprotein lipase from human postheparin plasma

open access: yesJournal of Lipid Research, 1977
Evidence is presented that hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL), purified from human postheparin plasma, can each hydrolyze both glyceryl trioleate and palmitoyl-CoA.
M L Baginsky, W V Brown
doaj   +1 more source

Frog foams and natural protein surfactants [PDF]

open access: yes, 2017
Foams and surfactants are relatively rare in biology because of their potential to harm cell membranes and other delicate tissues. However, in recent work we have identified and characterized a number of natural surfactant proteins found in the foam ...
Cooper, Alan   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Influence of Time–Activity Patterns on Indoor Air Quality in Italian Restaurant Kitchens

open access: yesAtmosphere
This study aims to delve deeper into the relationship between the professional activities carried out in restaurant kitchens and some key air pollutants. The ultrafine particles (UFPs), nitrogen dioxide (NO2), ozone (O3), Total Volatile Organic Compounds
Marta Keller   +14 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]

open access: yes, 2016
A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul   +13 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The influence of sodium-polyacrilic macromolecular chain length to the powder detergents secondary washing performances [PDF]

open access: yesHemijska Industrija, 2013
In order to investigate the influence of sodium-polyacrylate polymer as a co-builder in addition to the carbonate/zeolite builders in detergent builder system, secondary washing performances of powder laundry detergent containing equal percentage of ...
Milojević Vladimir S.   +3 more
doaj   +1 more source

The pH of the skin surface and its impact on the barrier function [PDF]

open access: yes, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Abeck D   +41 more
core   +1 more source

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