Results 201 to 210 of about 1,223,119 (315)

Measuring performance trajectories in lung cancer surgery: a longitudinal study using the French national hospital database from 2020 to 2024. [PDF]

BMJ Health Care Inform
Bernard A, Cottenet J, Tubert-Bitter P, Quantin C.   +3 more
europepmc   +1 more source

The effect of rock mass gradual deterioration on the mechanism of post-mining subsidence over shallow abandoned coal mines

, 2017
E. F. Salmi, Majidreza Nazem, M. Karakus
semanticscholar   +1 more source

Deterioration.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1968
openaire   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Early prediction of unplanned critical care transfers in children using EHR-based ensemble machine learning. [PDF]

JAMIA Open
Tweedy E, Mehta S, Mai MV, Ruiz V, Shi HL, Shaeffer GP, Nishisaki A, Muthu N, Tsui FR.   +8 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Multi-objective location-routing optimization of first-mile pre-cooling distribution center networks in the agricultural cold chain. [PDF]

PLoS One
Ying C, Kim YJ.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Diaphragm ultrasound and surface electromyography as predictors of clinical deterioration in acute exacerbations of COPD: a prospective observational study. [PDF]

ERJ Open Res
de Boer WS, Geerts L, Oppersma E, Edens MA, van den Berg JWK, Stigt JA, Slebos DJ, Duiverman ML.   +7 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source