Results 21 to 30 of about 89,515 (186)

Combining visual rating scales to identify prodromal Alzheimer's disease and Alzheimer's disease dementia in a population from a low and middle-income country

Frontiers in Neurology, 2022
BackgroundMany low- and middle-income countries, including Latin America, lack access to biomarkers for the diagnosis of prodromal Alzheimer's Disease (AD; mild cognitive impairment due to AD) and AD dementia.
Nilton Custodio, Nilton Custodio, Nilton Custodio, Nilton Custodio, Marco Malaga, Marco Malaga, Diego Chambergo-Michilot, Diego Chambergo-Michilot, Rosa Montesinos, Rosa Montesinos, Elizabeth Moron, Elizabeth Moron, Miguel A. Vences, Miguel A. Vences, Miguel A. Vences, José Carlos Huilca, José Carlos Huilca, José Carlos Huilca, David Lira, David Lira, David Lira, Virgilio E. Failoc-Rojas, Virgilio E. Failoc-Rojas, Monica M. Diaz, Monica M. Diaz   +24 more
doaj   +1 more source

Deterioro cognitivo asociado a radioterapia en tumores cerebrales [PDF]

, 2012
Introduction: There is limited knowledge about the influence on cognitive functions of the treatments for brain tumors based on radiotherapy (RT). Objective: To review the works conducted in recent years about the effects of RT on cognition in brain ...
Clavel, María, Pérez-Elvira, Rubén
core   +2 more sources

Cardiovascular risk factors and the allostatic interoceptive network in dementia

Alzheimer's &Dementia, Volume 21, Issue S2, December 2025.
Abstract Background Cardiovascular risk factors, such diabetes, hypertension, blood pressure, obesity, and smoking, are linked with allostatic‐interoception – the continuous monitoring of internal bodily states in anticipation of environmental demands. These risk factors are associated with dementia risk.
Jessica L Hazelton, Joaquín Migeot, Raul Gonzalez‐Gomez, Florencia Altschuler, Claudia Duran‐Aniotz, Olivia Wen, Dante Sebastián Galván Rial, Pablo Barttfeld, Vicente Medel, Cecilia Gonzalez Campo, Ana Maria Castro Laguardia, Hernan Hernandez, Carolina Gonzalez‐Silva, Olga Castaner, Kun Hu, Peng Li, María Isabel Behrens, Martin Alejandro Bruno, Juan Cardona, Nilton Custodio, Hernando Santamaria‐Garcia, Adolfo M Garcia, Maria Eugenia Godoy, José Alberto Ávila Funes, Marcelo Adrian Maito, Diana L Matallana, Bruce L. Miller, Francisco Lopera, Maira Okada de Oliveira, Stefanie Pina‐Escudero, Katherine L. Possin, Elisa de Paula França Resende, Pablo A Reyes, Andrea Slachevsky, Ana Luisa Sosa, Leonel Tadao Takada, Jennifer S. Yokoyama, Agustin Ibanez   +37 more
wiley   +2 more sources

Relationship between genetic risk and p‐tau concentration on cognitive performance in a multiethnic population from Peru [PDF]

Alzheimers Dement
Abstract Background The presence of APOE 4 is considered the main genetic risk factor for the development of dementia. Additionally, plasma p‐tau has been shown to be an important biomarker associated with Alzheimer's disease. However, these factors have been understudied in Latin American ethnic minorities, such as the Quechuas and Aymaras.
Rivera‐Fernandez C, Custodio N, Montesinos R, Muñoz‐Najar A, Reyes‐Dumeyer D, Tosto G, Soto‐Añari M.   +6 more
europepmc   +2 more sources

Association between brain structure imaging and health factors in a low education cohort [PDF]

Alzheimers Dement
Abstract Background Dementia is rising globally, with a significant impact in Latin America. Low education has been associated with reduced cognitive reserve and structural brain changes, increasing vulnerability to neurodegeneration. However, the factors influencing these brain alterations remain an emerging area of research.
Brown G, Bustamante‐Paytan D, Huilca J, Albujar‐Pereira M, Aguero K, Verastegui G, Yauri Z, Bartolo P, Bendezu D, Lipa‐Pari K, Montesinos R, Custodio N.   +11 more
europepmc   +2 more sources

Implementing a Training Program for Cognitive and Neuropsychological Assessments in a Latin America country [PDF]

Alzheimers Dement
Abstract In the coming decades, the number of dementia cases is projected to increase worldwide. This public health issue will significantly impact low‐ and middle‐income countries, such as those in Latin America, due to their aging populations.
Verastegui G, Bustamante‐Paytan D, Montesinos R, Custodio N, Tosto G.   +4 more
europepmc   +2 more sources

Impacto del deterioro cognitivo sobre la salud oral en personas mayores

European Journal of Health Research, 2018
El deterioro cognitivo y la demencia son trastornos que se caracterizan por una disminución de la cognición que afecta a uno o más aspectos de la misma, llegando a interferir con las actividades de la vida diaria de la persona.
Ana Adamuz Jiménez, Antonio García Rubio, María Cristina Ibáñez Romero   +2 more
doaj   +1 more source

Establishment of a Community Advisory Board in Lima, based on the adaptation of the Patient Advisor Toolkit to enhance recruitment in dementia research [PDF]

Alzheimers Dement
Abstract Background Community Advisory Boards (CABs) are formal groups of community members who collaborate with research teams. The establishment of CABs have been shown to be an effective strategy for enhancing community engagement in research. This study aims to illustrate the process of establishing a Community Advisory Board in Lima, Peru, based ...
Custodio B, Montesinos R, Huilca J, Bustamante‐Paytan D, Agüero‐Flores K, Verastegui G, Malaga M, Custodio N.   +7 more
europepmc   +2 more sources

Neurologists’ perceptions about the readiness for implementing anti‐amyloid drugs for Alzheimer's disease in Peru [PDF]

Alzheimers Dement
Abstract Background Alzheimer's disease (AD) is a neurodegenerative disease affecting millions of people worldwide. This situation is particularly severe in low‐ and middle‐income countries, where numerous barriers hinder timely diagnosis and treatment.
Custodio B, Montesinos R, Huilca J, Agüero‐Flores K, Bustamante‐Paytan D, Chambergo‐Michilot D, Verastegui G, Malaga M, Rojas M, Camargo I, Bayona W, Custodio N.   +11 more
europepmc   +2 more sources

Clinical characterization of probable Dementia with Lewy Bodies based on the initial clinical presentation in a Latin American Low‐ and Middle‐ Income Country [PDF]

Alzheimers Dement
Abstract Background Dementia with Lewy Bodies (DLB) is a specific type of dementia associated with the accumulation of alpha‐synuclein protein in the brain. The disease often presents heterogeneously in its early stages, and little is known about how this variability affects its progression.
Custodio N, Malaga M, Bustamante‐Paytan D, Huilca J, Aguero K, Verastegui G, Bartolo P, Bendezu D, Yauri Z, Montesinos R.   +9 more
europepmc   +2 more sources