Results 181 to 190 of about 2,993,437 (368)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Determinants of audit fees in developing countries: Evidence from Egypt

, 2020
Walid Elgammal, Marwa Gharzeddine
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Understanding digital health literacy as a structural determinant of health and public health capability. [PDF]

BMC Glob Public Health
Wamala-Andersson S, Uitto M, Diop-Christensen A, Hidalgo IR, Thorup CB, Heß F, Gonzalez MP.   +6 more
europepmc   +1 more source

Sex Determination [PDF]

Postgraduate Medical Journal, 1932
openaire   +2 more sources

Determinants and Utilization of Maternal Health Care Services in Urban Slums of an Industrialized City, in Western India

, 2020
Sandeep Sharma, Partha Sarathi Mohanty, Ruchi Omar, Ankit Viramgami, Namita Sharma   +4 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Waist circumference is an important determinant of relative muscle strength in patients with type 2 diabetes mellitus: Erratum. [PDF]

J Chin Med Assoc
Chiang YL, Su GY, Tsai SC, Chen CN, Hwu CM, Wu TH.   +5 more
europepmc   +1 more source

Determinants of puerperal sepsis among postpartum women: a case–control study in East Shoa Zone public hospitals, Central Ethiopia [PDF]

Befekadu Tesfaye Oyato, Tirunesh Debele, Dejene Edosa, Husen Zakir Abasimel, Mukemil Awol, Eleni Tesfaye Kebede, Andualem Gezahagn, Adugna Alemu Desta, Fikadu Tolesa Alemu, Samuel Boja Asfaw   +9 more
openalex   +1 more source

Phosphate Transporter PstSCAB of Campylobacter jejuni Is a Critical Determinant of Lactate-Dependent Growth and Colonization in Chickens

, 2020
Ritam Sinha, Rhiannon M. LeVeque, Marvin Q. Bowlin, Michael J. Gray, Victor J. DiRita   +4 more
openalex   +2 more sources