Results 281 to 290 of about 1,997,664 (317)

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Adding employment status in the medical record demonstrates its importance as a social determinant of health. [PDF]

JAMIA Open
Breeher LE, Westphal S, Green T, Abbas A, Cowl CT.   +4 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Disc deformation as a potential biomarker of nonspecific low back pain. [PDF]

Sci Rep
Lagerstrand KM, Hebelka H, Brisby H, Waldenberg C.   +3 more
europepmc   +1 more source

Uncovering bifurcation behaviors of biochemical reaction systems from network topology. [PDF]

Sci Rep
Huang YJ, Okada T, Mochizuki A.
europepmc   +1 more source

Correction: Data-driven machine learning algorithm model for pneumonia prediction and determinant factor stratification among children aged 6-23 months in Ethiopia. [PDF]

BMC Infect Dis
Demsash AW, Abebe R, Gezimu W, Kitil GW, Tizazu MA, Lambebo A, Bekele F, Alemu SS, Jarso MH, Dube GN, Wedajo LF, Purohit S, Kalayou MH.   +12 more
europepmc   +1 more source

Associations Between Head Motion, Age, and Psychiatric Diagnoses in a Large-Scale Developmental Sample. [PDF]

Biol Psychiatry Glob Open Sci
Power J, Liston C.
europepmc   +1 more source

Health promotion in the algorithmic age: recognizing the information environment as a determinant of health. [PDF]

Health Promot Int
Purnat TD, Wilhelm E, White BK, Okan O, Rosario R, Scales D.   +5 more
europepmc   +1 more source

Fifteen Years of PNPLA3: Transforming Hepatology Through Human Genetics. [PDF]

Liver Int
Romeo S, Valenti L.
europepmc   +1 more source