Results 71 to 80 of about 1,997,664 (317)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Determinant Sums for Undirected Hamiltonicity

open access: yes, 2010
We present a Monte Carlo algorithm for Hamiltonicity detection in an $n$-vertex undirected graph running in $O^*(1.657^{n})$ time. To the best of our knowledge, this is the first superpolynomial improvement on the worst case runtime for the problem since
Björklund, Andreas
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

How Iranian women conceptualize mental health: an explanatory model.

open access: yesIranian Journal of Public Health, 2014
In Iran, more than 25% of women suffer from mental disorders. Mental disorders and subclinical problems are associated with socioeconomic problem. At the community level, mental health promotion can reduce social damage.
Arash Mirabzadeh   +4 more
doaj  

Determinants of Distribution Logistics in the Construction Industry

open access: yesOpen Engineering, 2017
Global business is currently still influenced by the economic crisis and the economic development in each country of the EU. The construction sector is among the most affected sectors of the national economies.
Bukova Bibiana   +2 more
doaj   +1 more source

Abstract Harmonic Analysis on the General Linear Group GL(n,R) [PDF]

open access: yes, 2014
Consider the general linear group, which is not connected but rather has two connected components, the matrices with positive determinant and the ones with negative determinant. Consider the Iwasawa decomposition of its special linear group. We adopt the
El-Hussein, Kahar
core  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Evaluation of socioeconomic factors in injured children at Mousavi and Valiasr hospitals of Zanjan

open access: yesSalāmat-i ijtimā̒ī, 2016
Background and Objective: Injury is one of the causes of morbidity and mortality that deprives the injured individuals of a normal life but also imposes high emotional and financial costs for the patients and their family. This study was done in order to
Maryam Hasaniha   +3 more
doaj  

A Determinate Logic [PDF]

open access: yesNagoya Mathematical Journal, 1968
Let L be a fixed language and K be a set of structures related to L. A sentence in L is said to be K-valid if and only if for every structure in K,
openaire   +4 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

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