Results 121 to 130 of about 1,843,126 (299)

Exploring a Novel Family of Appell Polynomials Associated with Gould–Hopper–Fubini Polynomials

open access: yesMathematics
In this paper, we establish a new hybrid class of special polynomials, the Gould–Hopper–Fubini-based Appell polynomials. Using the monomiality principle, we derive their generating function and explore related properties and identities.
F. Gassem   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Gram determinant for cell representations

open access: yesGulf Journal of Mathematics
We study a new family of cell modules over the Fuss–Catalan algebras, focusing on the irreducibility of modules labeled by certain words. We define diagrammatic bases for these modules, compute their dimensions, define associated Gram matrices, and derive closed-form expressions for their determinants.
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

On the properties and algebraic features of extended multivariate Hermite-based Appell polynomials

open access: yesDemonstratio Mathematica
This paper introduces a new family of multivariate Hermite-based Appell polynomials with a one-parameter extension, defined through an appropriate generating function.
Zayed Mohra   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Temperature states on loop groups, boson-fermion correspondence, and a determinant identity

open access: yes, 1991
The boson-fermion correspondence for the representation of the CAR algebra over L2(S1,C) defined by the (τ, β) KMS state with chemical potential μ is considered and the non-bijectivity shown.
Watling, Neil A
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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