Results 41 to 50 of about 4,466 (196)
Singular Loci of Ladder Determinantal Varieties and Schubert Varieties
Journal of Algebra, 2000 The authors give an interpretation of ``ladder determinantal varieties'' as ``opposite cells'' in a suitable Schubert variety. It is then possible to determine the singular loci of these varieties. This leads to a conjecture on the irreducible components of the singular locus of a Schubert variety in the flag variety.
Gonciulea, N., Lakshmibai, V.
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Littlewood Complexes and Analogues of Determinantal Varieties [PDF]
International Mathematics Research Notices, 2014 31 pages; v2: added more details to proofs and calculations; v3: corrected typos and changed section/theorem ...
Sam, Steven V, Weyman, Jerzy
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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A note on linear subspaces of determinantal varieties
Le Matematiche, 1995 We use a geometrical approach to the study of the vector subspaces M in a determinantal variety in Hom(V,W) and derive conditions on dim(M) for M to belong to certain distingiushed classes of subspaces.
Riccardo Re
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Resultants of determinantal varieties
Journal of Pure and Applied Algebra, 2004 In this paper based on part of the author's doctoral dissertation, the author aims to extend the so called mixed resultant of \textit{I. M. Gelfand, M. M. Kapranov} and \textit{A. V. Zelevinsky} [Discriminants, resultants and multidimensional determinants.
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source