Results 61 to 70 of about 393 (215)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Orbit Structure of Grassmannian G2,m and a Decoder for Grassmann Code C(2, m). [PDF]
IEEE Trans Inf Theory, 2023 Piñero FL, Singh P.
europepmc +1 more source
Determinantal varieties over truncated polynomial rings
Journal of Pure and Applied Algebra, 2005 29 pages, 1 ...
Košir, Tomaž, Sethuraman, B.A.
openaire +3 more sources
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Divisor Class Groups of Ladder Determinantal Varieties
Journal of Algebra, 1996 Let \(X=(X_{ij})\) be an \(r\times s\) matrix of indeterminates over a field \(K\). A ladder \(L\) in \(X\) is a subset of \(X\) which satisfies the following condition: whenever \(X_{ij} \in L\) and \(X_{kl} \in L\) with \(i\leq k\) and \(j\leq l\), then \(X_{il} \in L\) and \(X_{kj} \in L\).
MOTWANI, JV, SOHONI, MA
openaire +2 more sources
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Codimension Two Determinantal Varieties with Isolated Singularities
MATHEMATICA SCANDINAVICA, 2014 We study codimension two determinantal varieties with isolated singularities. These singularities admit a unique smoothing, thus we can define their Milnor number as the middle Betti number of their generic fiber. For surfaces in $\mathsf{C}^4$, we obtain a Lê-Greuel formula expressing the Milnor number of the surface in terms of the second polar ...
Soares Ruas, Maria Aparecida +1 more
openaire +4 more sources
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source