Results 211 to 220 of about 2,911,566 (241)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Behavioral determinants of condom use and HIV/STI testing in Chile: a theory-driven mixed-methods study. [PDF]

open access: yesSci Rep
Duarte-Anselmi G   +3 more
europepmc   +1 more source

Global Analysis of the Co-Occurrence of Antimicrobial and Metal Resistance Genes in Bacterial Genomes From Dairy-Isolated Pathogens. [PDF]

open access: yesEnviron Microbiol
Almeida ACO   +8 more
europepmc   +1 more source

Psychosocial determinants of child cognitive development in sub-Saharan early childhood development centres: a systematic review protocol. [PDF]

open access: yesSyst Rev
Rantho KM   +9 more
europepmc   +1 more source

Determinants of the Uptake and Frequency of Use of a Web Portal Digital Health Intervention in Patients With Type 2 Diabetes and/or Coronary Heart Disease: Secondary Analysis of a Randomized Controlled Trial.

open access: yesJ Med Internet Res
Scholl M   +16 more
europepmc   +1 more source

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