Results 61 to 70 of about 264,302 (267)
Preventive Effect of Clofibrate on Neonatal Hyperbilirubinemia
Background: Neonatal jaundice is a common problem that can result in serious neurological side effect such as Kern icterus. Several drugs are used to prevent neonatal jaundice.
Yadollah Zahed Pasha +4 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Background: Malnutrition is a common clinical problem in critically ill patient at ICU. It has irreversible consequences for patients and causes heavy health care costs for the healthcare system. Nurses are the main responsible for providing nutritional
Atefeh Taherkhani +3 more
doaj
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Background Premenstrual syndrome (PMS) is a common issue that impacts many women, and a well-balanced diet can help alleviate PMS symptoms. Evidence suggests that dietary factors and eating disorders may influence PMS severity, yet the specific ...
Sara Mighani +4 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Social determination in the health of children born preterm: a scoping review [PDF]
Objective: to map scientific knowledge on the dimensions of the Social Determinants of Health in the health of children born preterm in the first two years of life.
Mariana Fuentes Mendoza Rodrigues Soares +5 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

