Results 251 to 260 of about 6,042,646 (342)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
PSI/Masc-Dsx Regulatory Network in Silkworm Sex Determination Pathway. [PDF]
InsectsTan C +7 more
europepmc +1 more source
Synchronous spectrofluorimetric determination of tryptophan and kynurenine in human plasma using hydroxypropyl-β-cyclodextrin complexation for investigating their role in major depressive disorder. [PDF]
Sci RepAlharbi A +4 more
europepmc +1 more source
Caenorhabditis tropicalis followed a unique evolutionary path to self-fertility. [PDF]
GeneticsKennedy J +6 more
europepmc +1 more source
Temperature-dependent sex expression in cucurbits and beyond: mechanisms, reproductive plasticity, and breeding implications. [PDF]
Front Plant SciTao Y +9 more
europepmc +1 more source
Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel. [PDF]
ElifeYang Z, Luo T, Zhang Y, Sun Y.
europepmc +1 more source