Results 31 to 40 of about 1,785,985 (267)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Can Individuals with 47,XYY Karyotypes Exist without Male Phenotype? A Narrative Literature Review and Case Report

Frontiers in Bioscience-Scholar
Background: The 47,XYY syndrome is a genetic condition found in about 1 in 1000 male children. The expected phenotype is male but could vary greatly.
Marcelo Jones Pires, Laura Coimbra Teixeira, Luise Longo Angeloni, Julia Londero Heleno, Mariana Romano, Marcio Lopes Miranda, Tarsis Paiva Vieira, Mara Sanches Guaragna, Beatriz Amstaldem Barros, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior   +10 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Effects of summer supplementation of Houttuynia cordata extract on growth performance, anti-inflammatory properties, and rumen fermentation in Guizhou black goats

Frontiers in Veterinary Science
The aim of this study was to examine the effects of supplementing Guizhou black goats with Houttuynia cordata extract (HCE) during summer on growth performance, anti-inflammatory activity, and rumen fermentation parameters. A completely randomized single-
Lingling Xie, Zhongling Jian, Mingyan Tang, Chen Li, Zhiyu Huang, Fu Wang, Ren Ou, Shengyong Lu   +7 more
doaj   +1 more source

Determinant identities [PDF]

Pacific Journal of Mathematics, 1993
The following generalization of a determinant formula proved by \textit{W. H. Mills}, \textit{D. P. Robbins} and \textit{H. Rumsey} jun. [Discrete Math. 67, 43-55 (1987; Zbl 0656.05006)] is proved. Let \(\Delta_ 0(u)=2\) and for \(j>0\) let \[ \Delta_{2j}(u)={(u+2j+2)_ j({1\over 2}u+2j+{3\over 2})_{j-1}\over(j)_ j\cdot({1\over 2}u+j+{3\over 2})_{j-1}} \
Andrews, George E., Burge, William H.
openaire   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Determining Environmental Determinism

Progress in Human Geography, 2012
This commentary is a direct response to the Forum article ‘Environmentalist thinking and/in geography’ by Radcliffe et al. (2010) . Two main problems are addressed: the perpetuation of a false analogy between cultural and biological evolution, and a misunderstanding of memes.
openaire   +5 more sources

Whole-genome sequencing and variants data of 304 indigenous goats from Southwest China

Scientific Data
Indigenous goats exhibit strong adaptability to remote environments and provide a vital source of protein for residents in impoverished regions. Whole-genome sequencing (WGS) data can elucidate the economic traits of these goats.
Jipan Zhang, Di Zhou, Rong Yang, Zhengang Guo, Xingzhou Tian, Yongju Zhao   +5 more
doaj   +1 more source