Results 201 to 210 of about 13,501,965 (257)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Study on the determination method of excitation load in electrical signal simulation for piezoelectric ultrasonic internal inspection of pipelines. [PDF]

Sci Rep
Xu G, Liu J, Wen Q, Zheng Y, Cai L.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Main Factors Affecting the Minimum Sampling Area Determination Method: Based on Research of the Shrub Layer in Island <i>Pinus massoniana</i> Forests. [PDF]

Biology (Basel)
Xiao J, Wen Q, Zhong Z, Xie Y, Wang Y, Cai X, Lin Y, Weng F, Ding G, Deng C.   +9 more
europepmc   +1 more source

A near-infrared spectroscopy-based end-point determination method for the blending process of Dahuang soda tablets. [PDF]

J Zhejiang Univ Sci B, 2020
Wu SJ, Qiu P, Li P, Li Z, Li WL.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

CW_ICA: an efficient dimensionality determination method for independent component analysis. [PDF]

Sci Rep
Yi Y, Billor N, Ekstrom A, Zheng J.
europepmc   +1 more source

A Rapid and High Throughput MIC Determination Method to Screen Uranium Resistant Microorganisms. [PDF]

Methods Protoc, 2020
Agarwal M, Rathore RS, Chauhan A.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Does LDL-C determination method affect statin prescribing for primary prevention? A register-based study in Southern Denmark. [PDF]

Eur Heart J Cardiovasc Pharmacother
Pottegård A, Gerdes LU, Wetche JL, Thompson W.   +3 more
europepmc   +1 more source