Results 141 to 150 of about 30,754 (311)

Definite Determiners in French and its Czech Equivalents

open access: yes, 2013
The theme of the Bachelor´s thesis are definite determiners in French and its Czech equivalents. The aim of the thesis that is based on the specialized literature is to describe their morphological, syntactic and semantic properties including their ...
KRONIKOVÁ, Andrea
core  

The vulnerability of gender on determiners in L1, 2L1 and L2 acquisition

open access: yesBucharest Working Papers in Linguistics, 2009
The acquisition of gender has been reported to be problematic for some groups of learners acquiring Germanic or Romance languages. It has been shown that L1 learners do better in gender acquisition than others, like bilingual children, child L2 learners ...
Elisabeth van der Linden, Aafke Hulk
doaj  

Edge-determining sets and determining index

open access: yesInvolve, a Journal of Mathematics
A graph automorphism is a bijective mapping of the vertices that preserves adjacent vertices. A vertex determining set of a graph is a set of vertices such that the only automorphism that fixes those vertices is the identity. The size of a smallest such set is called the determining number, denoted Det$(G)$. The determining number is a parameter of the
Cockburn, Sally, McAvoy, Sean
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Demonstrating understanding: the role of demonstrative determiners in deepening phonetic and semantic processing

open access: yes
This experiment examines the difficulty associated with processing definite determiners vs. demonstrative determiners in English, using pupillometry, phoneme monitoring, and eye-tracking.
Rachel Smith   +2 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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