Results 251 to 260 of about 30,754 (311)

Marked unergatives: Syntactic ergativity and nominalizations. [PDF]

Nat Lang Linguist Theory
Hopperdietzel J, Alexiadou A.
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Brown Bear, Brown Bear, What Do You See? Speakers Use More Redundant Color Adjectives When Speaking to Children Than Adults. [PDF]

Open Mind (Camb)
Taliaferro M, Schulz L.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The content of pronouns: evidence from focus

, 2009
Sauerland, Uli
core  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Genome assemblies for Chromidotilapia guntheri (Teleostei: Cichlidae) identify a novel candidate gene for vertebrate sex determination, RIN3. [PDF]

Front Genet
Behrens KA, Koblmüller S, Kocher TD.
europepmc   +1 more source

Towards a speech-based digital biomarker for cognitive impairment: speech as a proxy for cognitive assessment. [PDF]

NPJ Digit Med
Heitz J, Engler IM, Langer N.
europepmc   +1 more source

Adversarial Text Generation using Large Language Models for Dementia Detection. [PDF]

Proc Conf Empir Methods Nat Lang Process
Zhu Y, Lin N, Balivada KS, Haehn D, Liang X.   +4 more
europepmc   +1 more source

The role of word form in gender processing during lexical access: A theoretical review and novel proposal in language comprehension. [PDF]

Psychon Bull Rev
Sá-Leite AR, Lago S.
europepmc   +1 more source