Results 111 to 120 of about 291,001 (382)

6R/S-deutero-α-d-mannopyranoside 1-phosphate

Molbank, 2019
6R/S-deutero-α-d-mannopyranoside 1-phosphate was synthesised from a C6 aldehydic mannose thioglycoside donor in four steps. Using NaBD4 as the reductant, isotopic enrichment at C6 was achieved and the resultant C6-deuterated material was converted ...
Sanaz Ahmadipour, Gavin J. Miller
doaj   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Hydrogeochemical characteristics of the River Sava watershed in Slovenia

Geologija, 2007
The River Sava is a typical HCO3- – Ca2+ – Mg2+ River. Total alkalinity increases in the part of the watershed composed of carbonate and clastic rocks, which are less resistant to weathering processes.
Tjaša Kanduč, Nives Ogrinc
doaj  

Deuterium retention in tungsten oxide: the role of oxide damage

Nuclear Fusion
Tungsten (W) is a common plasma-facing material in nuclear fusion devices. It readily oxidizes in the presence of oxygen, forming tungsten oxides, particularly WO _3 , which may modify deuterium retention.
Mykola Ialovega, Celine Martin, Cédric Pardanaud, Elodie Bernard, Martiane Cabié, Andrea Campos, Christian Grisolia, Marco Minissale, Thomas Neisius, Thierry Angot, Régis Bisson   +10 more
doaj   +1 more source

Iridium-Catalysed ortho-Directed Deuterium Labelling of Aromatic Esters—An Experimental and Theoretical Study on Directing Group Chemoselectivity

Molecules, 2015
Herein we report a combined experimental and theoretical study on the deuterium labelling of benzoate ester derivatives, utilizing our developed iridium N-heterocyclic carbene/phosphine catalysts.
Jennifer Devlin, William. J. Kerr, David M. Lindsay, Timothy J. D. McCabe, Marc Reid, Tell Tuttle   +5 more
doaj   +1 more source

Studies of Tryptophans in Membrane- Spanning WALP Peptides by Deuterium NMR Spectroscopy [PDF]

, 2000
WALP pep tides of sequence acetyl-Gly-Trp-Trp-(Leu-Ala)-Trp-Trp-Ala-ethanolamine insert into lipid bilayers as membrane-spanning a-helices and modulate the lipid phase behavior as functions of n and the lipid acyl chain length.
Reed, Nichole
core   +2 more sources

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

First results of laser-induced desorption - quadrupole mass spectrometry (LID-QMS) at JET

Nuclear Fusion
The paper reports the first demonstration of in situ laser-induced desorption — quadrupole mass spectrometry (LID-QMS) application on a large scale fusion device performed in summer 2023. LID-QMS allows direct measurements of the fuel inventory of plasma
M. Zlobinski, G. Sergienko, I. Jepu, C. Rowley, A. Widdowson, R. Ellis, D. Kos, I. Coffey, M. Fortune, D. Kinna, M. Beldishevski, A. Krimmer, H.T. Lambertz, A. Terra, A. Huber, S. Brezinsek, T. Dittmar, M. Flebbe, R. Yi, R. Rayaprolu, J. Figueiredo, P. Blatchford, S. Silburn, E. Tsitrone, E. Joffrin, K. Krieger, Y. Corre, A. Hakola, J. Likonen, the Eurofusion Tokamak Exploitation Team, JET Contributors   +30 more
doaj   +1 more source

Expanding the Isotopic Toolbox to Track Monarch Butterfly (Danaus plexippus) Origins and Migration: On the Utility of Stable Oxygen Isotope (δ18O) Measurements

Frontiers in Ecology and Evolution, 2019
The measurement of naturally occurring stable hydrogen (δ2H) and carbon (δ13C) isotopes in wings of the eastern North American monarch butterflies (Danaus plexippus) have proven useful to infer natal origins of individuals overwintering in Mexico.
Keith A. Hobson, Keith A. Hobson, Kevin J. Kardynal, Geoff Koehler   +3 more
doaj   +1 more source