Results 211 to 220 of about 878,178 (411)

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Erratum zu: Problematische Nutzung digitaler Medien und Gesundheitskompetenz von Schülerinnen und Schülern in Deutschland. Befunde der HBSC-Studie 2022. [PDF]

open access: yesBundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Dadaczynski K   +9 more
europepmc   +1 more source

From small business promotion to creating an entrepreneurial society [PDF]

open access: yes
Mittelstandspolitik, Unternehmer, Wissenstransfer, EU-Staaten, Deutschland, Small business policy, Entrepreneurs, Knowledge transfer, EU countries ...
David B. Audretsch
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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