Results 301 to 310 of about 14,908,548 (354)

Designing DECIdE Together: An Interprofessional and Patient-Centered Approach to Develop a Patient Decision Aid for Drugs in Primary Care (DECIsion in hEalth)

Élodie Charuel, Thibault Ménini, Sarah Chateauneuf, Léa Mathieu, Mélody Mailliez, Céline Deveuve-Murol, Marielle Duchassaing, Sabrina Bedhomme, Philippe Vorilhon, Hélène Vaillant-Roussel   +9 more
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Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo). [PDF]

Comput Struct Biotechnol J
Vidal-Henriquez E, Holder T, Lee NF, Pompe C, Teese MG.   +4 more
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Prediction of Small-Molecule Developability Using Large-Scale In Silico ADMET Models.

Journal of Medicinal Chemistry, 2023
Early in silico assessment of the potential of a series of compounds to deliver a drug is one of the major challenges in computer-assisted drug design. The goal is to identify the right chemical series of compounds out of a large chemical space to then ...
Maximilian Beckers, Noé Sturm, F. Sirockin, N. Fechner, N. Stiefl   +4 more
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Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin.

Journal of Medicinal Chemistry, 2023
Corramycin 1 is a novel zwitterionic antibacterial peptide isolated from a culture of the myxobacterium Corallococcus coralloides. Though Corramycin displayed a narrow spectrum and modest MICs against sensitive bacteria, its ADMET and physchem profile as
Stéphane Renard, Stéphanie Versluys, Thomas Taillier, Nelly Dubarry, Corinne Leroi-Geissler, A. Rey, Emilie Cornaire, Sylvie Sordello, Jean-Christophe B Carry, Odile Angouillant-Boniface, T. Gouyon, Fabienne Thompson, Gilles Lebourg, Victor Certal, Laszlo Balazs, Esther Arranz, Gilles Doerflinger, F. Bretin, Vincent Gervat, Eric Brohan, Volker Kraft, Xavier Boulenc, Cécile Ducelier, E. Bacqué, C. Couturier   +24 more
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Developability-driven piecewise approximations for triangular meshes

ACM Transactions on Graphics, 2022
We propose a novel method to compute a piecewise mesh with a few developable patches and a small approximation error for an input triangular mesh. Our key observation is that a deformed mesh after enforcing discrete developability is easily partitioned ...
Zheng-Yu Zhao, Qing Fang, W. Ouyang, Zheng Zhang, Ligang Liu, Xiaoming Fu   +5 more
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Developers, Developers, Developers

New Electronics, 2019
At this year’s GPU Developer’s Conference, NVIDIA’s CEO Jensen Huang took to the stage with a series of announcements.
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Early Development

SSRN Electronic Journal, 1994
Long-term economic development involves four fundamental processes: the exploitation of increasing returns to specialization, the transition from household to market production, knowledge and human capital accumulation, and industrialization. In this paper, we integrate these processes into a coherent framework for thinking about economic history.
Goodfriend, Marvin, McDermott, John
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Developing human nature: “Development to” versus “Development from?”

Developmental Psychobiology, 2007
AbstractEvolutionary psychology (EP) emphasizes that socio‐cultural experiences are constrained by the characteristics of the individual. Therefore, cultural experience acts on a nervous system biased to respond to in particular ways (i.e., human nature).
George F, Michel, Amber N, Tyler
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