Results 71 to 80 of about 1,487,569 (314)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

False issues in the debate on interest rate policies in less developed countries

open access: yesPSL Quarterly Review, 2013
The work argues that many of the issues that have figured in interest rate policy discussions in the context of less developed countries are false, arising partly from terminological nuances, but largely from incorrect premises and approaches.
D. KHATKHATE
doaj   +1 more source

First birth trends in developed countries [PDF]

open access: yes
Levels and trends of various facets concerning first births are continuously changing. The evidence confirms that the postponement of first births is an ongoing and persisting process which started in western countries among cohorts of the 1940s, but ...
Jean-Paul Sardon, Tomas Frejka
core  

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Does population ageing impact inflation?

open access: yesStanovništvo, 2021
Modern society is characterised by clear and distinct demographic processes, such as the constant decline in the number of children born and the ageing population in developed countries, resulting from complex biological, economic, social, political ...
Marija Radulović, Milan Kostić
doaj  

The double-bind of oil and aid – a way out

open access: yesPSL Quarterly Review, 2013
In the search for a solution of the present oil problem very little attention is apparently being paid by the developed nations to the plight of the non-oil producing developing countries (LDCs).
G.C. ABBOT
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

Trends in nontariff barriers of developed countries : 1966-1986 [PDF]

open access: yes
While major concerns have been expressed about the spread of non-tariff barriers (NTBs) in developing countries, the lack of empirical information on the dimensions of the increase has affected the related policy debates.
Yeats, Alexander, Laird, Sam
core  

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Asia-Pacific review of the implementation of the Brussels programme of action for the least developed countries for the decade 2001-2010

open access: yes, 2006
This report reviews the implementation of the Programme of Action in the specific Commitments which are especially relevant to the least developed countries of Asia and the Pacific and where regional cooperation can be most effective, namely, (i ...
United Nations Development Programme (UNDP)   +1 more
core  

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