Results 221 to 230 of about 1,276,409 (316)

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

The impact of ambient temperature on preeclampsia admissions in cold regions of developing countries: a distributed lag analysis in Harbin, China. [PDF]

BMC Pregnancy Childbirth
Wang Q, Yu C, Sun Y, Zhang Y, Chen R, Zhang H, Song T, Yuan J.   +7 more
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Efficiency of health systems in developing countries: the case of West African countries. [PDF]

Health Econ Rev
Akoetey K, Viallefont A.
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Bridging the sustainability gap: the impact of business-government relations on corporate carbon monitoring in developing countries. [PDF]

Carbon Balance Manag
Khan K, Khan WA, Yan Y, Khokhar M, Rehman MZ, Ullah A.   +5 more
europepmc   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

Advanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu, Hongmin Liu, Long Fan, Huakun Liu, Shixue Dou, Guoxiu Wang, Nana Wang, Zhongchao Bai   +7 more
wiley   +1 more source

Impact of technological acceptance on application-based engagement among type 2 diabetes patients: local insights and implications for developing countries. [PDF]

J Pharm Policy Pract
Tahira A, Mohamed MHN, Elnaem MH, Hashmi FK, Bukhari NI.   +4 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Interest in long-acting injectable ART among adolescents with perinatally acquired HIV in Cameroon: Implications for implementation in developing countries. [PDF]

PLOS Glob Public Health
Bouba Y, Ka'e AC, Ayafor C, Forgwei L, Gabisa JE, Mabongo D, Nka AD, Mejane RE, Tetang SN, Kamgaing RS, Ateba FN, Fainguem NN, Tchouaket MCT, Takou D, Kamgaing N, Menye MA, Noukayo F, Semengue ENJ, Basseck RW, Wiadamong A, Gnambi AR, Eyenga C, Etame NK, Ngueko AMK, Fotso LGM, Yimga JF, Beloumou GA, Chenwi CA, Sosso SM, Ketchaji A, Tchidjou HK, Ekane GEH, Koki PN, Armenia D, Colizzi V, Ajeh RA, Russo G, D'amelio S, Ceccherini-Silberstein F, Perno CF, Ndjolo A, Santoro MM, Fokam J.   +42 more
europepmc   +1 more source