Results 41 to 50 of about 3,763,639 (307)

Increasing European Support for Neglected Infectious Disease Research

open access: yesComputational and Structural Biotechnology Journal, 2017
Neglected infectious diseases (NIDs) are a persistent cause of death and disability in low-income countries. Currently available drugs and vaccines are often ineffective, costly or associated with severe side-effects.
Ole F. Olesen, Marit Ackermann
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Developing biobanks in developing countries.

open access: yesJournal of global health, 2011
We call for the development of human biobanks in developing countries and describe several examples from low income countries which are already building their own biobanks. Developing human biobanks in developing countries requires strengthening of the research capacity to use the new technologies, as well as a shift in research investment priorities ...
Igor Rudan   +2 more
openaire   +3 more sources

Building financial institutions in developing countries [PDF]

open access: yes, 1999
Financial development and financial institution building are important prerequisites for economic growth. However, both the potential and the problems of institution building are still vastly underestimated by those who design and fund institution ...
Schmidt, Reinhard H., Winkler, Adalbert
core  

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Drinking water quality assessment and corrosion mitigation in the hospital water supply system of Chacas Village (Peru)

open access: yesRevista Ambiente & Água, 2014
Rural hospitals in developing countries often lack appropriate water treatments to assure their water needs. In these facilities, due to water different uses and its use with medical equipment, water quality problems can cause very hazardous situations ...
Riccardo Bigoni   +3 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Does socioeconomic status of farmers determine the adoption of forest landscape restoration practices? Evidence from Central Togo

open access: yesSustainable Environment
Forest Landscape Restoration (FLR) has gained significant attention as a global initiative to address forest and land degradation. While most studies emphasize the diverse benefits of FLR, very few have investigated the extensive nature of its adoption ...
Hamza Moluh Njoya   +5 more
doaj   +1 more source

Modeling freshwater snail habitat suitability and areas of potential snail-borne disease transmission in Uganda

open access: yesGeospatial Health, 2006
Geographic information system (GIS)-based modeling of an intermediate host snail species’ environmental requirements using known occurrence records can provide estimates of its spatial distribution.
A.S. Stensgaard   +4 more
doaj   +1 more source

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