Results 41 to 50 of about 583,379 (310)

Helmets and traffic injury outcomes: Findings from a setting lacking legislation on proper wearing and quality assessment

Cogent Medicine, 2018
Objective: We assessed the effectiveness of helmet wearing for improving traffic injury outcomes in a setting lacking legislations on proper wearing and quality assessment of helmets.
Junaid A. Bhatti, Junaid A. Razzak, Uzma R. Khan, Rashid Jooma   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Prevalence and risk factors for asthma among adults in Tanzania

Clinical Epidemiology and Global Health
Background: Limited information exists on the magnitude of asthma and associated factors in Africa. In Tanzania, very few studies have conducted epidemiological investigation of adult asthma.
Hussein Hassan Mwanga, Simon Henry David Mamuya, Bente Elisabeth Moen, Cecilie Svanes   +3 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Strengthening national health research systems in the WHO African Region – progress towards universal health coverage

Globalization and Health, 2019
Background Health challenges and health systems set-ups differ, warranting contextualised healthcare interventions to move towards universal health coverage.
Simbarashe Rusakaniko, Michael Makanga, Martin O. Ota, Moses Bockarie, Geoffrey Banda, Joseph Okeibunor, Francisca Mutapi, Prosper Tumusiime, Thomas Nyirenda, Joses Muthuri Kirigia, Juliet Nabyonga-Orem   +10 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Research during medical school: is it particularly difficult in developing countries compared to developed countries?

Advances in Medical Education and Practice, 2017
Manjunath Siddaiah-Subramanya,1,2 Harveen Singh,3 Kor Woi Tiang1,2 1Department of Surgery, Logan Hospital, 2Department of Medicine, Griffith University, 3Department of Gastroenterology, Lady Cilento Children’s Hospital, Brisbane, QLD, Australia ...
Siddaiah-Subramanya M, Singh H, Tiang KW
doaj  

Improving Service Quality Of Delivery Services Based On Heterogeneous Customer Behavior In A Developing Country: A Context During Covid-19 [PDF]

, 2022
Rahmat Hidayat Muslimin, Armin Darmawan, Syamsul Bahri, Amrin Rapi   +3 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source