Results 91 to 100 of about 247,491 (312)

Combinational Equivalence Checking Using Satisfiability and Recursive Learning

open access: yes, 1999
The problem of checking the equivalence of combinational circuits is of key significance in the verification of digital circuits. In recent years, several approaches have been proposed for solving this problem.
Thomas Glass   +3 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Design, analysis and evaluation of routing and channel assignment algorithms for wireless mesh networks

open access: yes, 2011
In this thesis we describe the efforts we made for designing, developing and analyzing new routing and channel assignment algorithms for wireless mesh networks.
Di Stasi, Giovanni
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Decentralized Analysis of Brain Imaging Data: Voxel-Based Morphometry and Dynamic Functional Network Connectivity

open access: yesFrontiers in Neuroinformatics, 2018
In the field of neuroimaging, there is a growing interest in developing collaborative frameworks that enable researchers to address challenging questions about the human brain by leveraging data across multiple sites all over the world.
Harshvardhan Gazula   +9 more
doaj   +1 more source

Development of a new algorithm for power flow analysis

open access: yesInternational Journal of Electrical Power & Energy Systems, 2011
This paper presents a new iterative solution technique for power flow analysis to reduce the computation complexity, hence time of the conventional solution techniques. In the proposed method, the impedance matrix has been used instead of admittance matrix.
Sourav Mallick   +4 more
openaire   +1 more source

A distributed framework for semi-automatically developing architectures of brain and mind

open access: yes, 2005
Developing comprehensive theories of low-level neuronal brain processes and high-level cognitive behaviours, as well as integrating them, is an ambitious challenge that requires new conceptual, computational, and empirical tools.
Lane, PCR, Gobet, F
core  

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