Results 121 to 130 of about 46,745,990 (349)
The East Midlands public procurement opportunities plan [PDF]
, 2009 Public sector procurement activity accounts for a significant share of economic activity. This document sets out how the East Midlands can maximize the commercial benefits of these opportunities and contribute to the delivery of public policy in the ...
East Midlands Development Agency
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2006 GravitasFall_newsletter_pdf.pdf: 255 downloads, before Oct.
Institute for Community College Development
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Xiehe Yixue ZazhiShort stature is a disease that affects children's physical and psychological health, closely associated with lifestyle factors such as diet, physical activity, and sleep.
China Behavioral Medical Research Center for Growth and Development, Behavioral Medicine Branch of Chinese Medical Association Committee on Growth, Development and Metabolism, China Maternal and Child Health Research Association
doaj +1 more source
Physical Review B (Condensed Matter), 1988 Chengteh Lee, Weitao Yang, R. Parr
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
SDC Submission to NI Assembly Environment Committee : inquiry into climate change [PDF]
, 2012 This document is the Sustainable Development Commission Northern Ireland’s submission to the Northern Ireland Assembly Environment Committee inquiry into climate change.Publisher ...
Sustainable Development Commission Northern Ireland
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Development and testing of a general amber force field
Journal of Computational Chemistry, 2004 Junmei Wang +4 more
semanticscholar +1 more source