Results 161 to 170 of about 46,058,019 (378)

Consensus on the Establishment and Operational Standards of Standardized Growth-and-Development Medical Centers Based on Active Health Principles (2025)

open access: yesXiehe Yixue Zazhi
With accelerated socioeconomic development and structural lifestyle changes, childhood and adolescent growth and developmental disorders in China have exhibited increasing complexity and a trend toward earlier onset, while the incidence of certain ...
China Behavioral Medical Research Center for Growth and Development, Behavioral Medicine Branch of Chinese Medical Association   +1 more
doaj   +1 more source

The Theory of Economic Development

open access: yes, 2017
J. Schumpeter, Ursula Backhaus
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

The East Midlands public procurement opportunities plan [PDF]

open access: yes, 2009
Public sector procurement activity accounts for a significant share of economic activity. This document sets out how the East Midlands can maximize the commercial benefits of these opportunities and contribute to the delivery of public policy in the ...
East Midlands Development Agency
core  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Declaração de Fortaleza

open access: yesSustentabilidade em Debate, 2010
Declaração de ...
2010 International Conference on Climate Sustainability and Development in Semi-arid Regions
doaj  

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