Results 161 to 170 of about 12,117,877 (287)

Emergence of Tigecycline-Resistant Pseudomonas aeruginosa Harbouring tmexC6D6-toprJ1b From Hospital Sewage in Japan. [PDF]

open access: yesEnviron Microbiol Rep
Maehana S   +10 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

MANAGEMENT OF SCHIZOPHRENIA IN ADULTS [PDF]

open access: yesMalaysian Family Physician, 2011
DEVELOPMENT GROUP CPG MANAGEMENT OF SCHIZOPHRENIA MOH MALAYSIA
doaj  

Ectodysplasin-A (EDA) Signaling Cross-Talk in Skeletogenesis. [PDF]

open access: yesCalcif Tissue Int
Ahi EP, Moustakas-Verho J, Singh P.
europepmc   +1 more source

Sleep, Development, and Human Health [PDF]

open access: bronze, 2007
Mark S. Blumberg   +2 more
openalex   +1 more source

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