Results 161 to 170 of about 26,389,358 (331)
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Multiple causal pathways of high-quality development for semiconductor enterprises in China. [PDF]
Li S, Yang X.
europepmc +1 more source
Epithelial-Mesenchymal Transitions in Development and Disease
J. P. Thiery +5 more
semanticscholar +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Research advances in rumen development and regulatory mechanisms in young ruminants. [PDF]
Yu G, Wu D.
europepmc +1 more source
Development of the Initial Surveys for the All of Us Research Program
Robert M. Cronin +29 more
openalex +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Developing an Evaluation Framework Based on Entrustable Professional Activities for Advanced Practice Nurses in China. [PDF]
Han S +6 more
europepmc +1 more source

