Results 171 to 180 of about 46,058,019 (378)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Gravitas, Fall 2006 [PDF]

, 2006
GravitasFall_newsletter_pdf.pdf: 255 downloads, before Oct.
Institute for Community College Development
core   +1 more source

The development of the chick : an introduction to embryology / Frank R. Lillie.

, 1936
Frank Lillie
openalex   +2 more sources

Development and testing of a general amber force field

Journal of Computational Chemistry, 2004
Junmei Wang, R. Wolf, J. Caldwell, P. Kollman, D. Case   +4 more
semanticscholar   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Submission from the Sustainable Development Commission Scotland on the Scottish Government's 'Energy efficiency action plan' [PDF]

, 2012
This letter is a response from the Sustainable Development Commission Scotland to the Scottish Government's 'Energy efficiency action plan'.Publisher ...
Sustainable Development Commission Scotland
core  

The Development of Doctrine [PDF]

, 1911
William Muir
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Declaração de Fortaleza Declaration of Fortaleza

Sustentabilidade em Debate, 2010
Declaração de FortalezaDeclaration of ...
2010 International Conference on Climate, Sustainability and Development in Semi-arid Regions
doaj  

Public Administration and Policy Development: A Case Book

, 1952
James W. Fesler, Harold Stein
openalex   +2 more sources