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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Net Present Value Impact of FDA's Phase 3 Waivers on Monoclonal Antibody Biosimilar Development. [PDF]

Biologics
Ranbhor R, Kulkarni P.
europepmc   +1 more source

Regional economic resilience and sustainable development: Does industrial diversity matter? [PDF]

PLoS One
Mu S.
europepmc   +1 more source

Does sports industry development improve regional public health? A cross-regional heterogeneous study in China. [PDF]

Front Public Health
Song S.
europepmc   +1 more source

The Current Landscape and Future Prospects of Vaccine Manufacturing in Africa: Challenges, Innovations, and Opportunities: A Narrative Review. [PDF]

Health Sci Rep
Chandipwisa C, Shimilimo A, Uwishema O, Onyeaka H.   +3 more
europepmc   +1 more source

Kindergarten development and fertility intention: an empirical study from China. [PDF]

Front Sociol
Wang J, Gao L, Wang G.
europepmc   +1 more source

Modified Dixon MRI to detect subclinical inflammation in clinically suspect arthralgia as a risk factor for rheumatoid arthritis development: should we image one or two hands? [PDF]

RMD Open
van der Kaaij D, Claassen S, van Steenbergen HW, Oei EHG, de Jong PHP, Reijnierse M, van der Helm-van Mil AHM.   +6 more
europepmc   +1 more source

Correction to "Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

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New Electronics, 2019
At this year’s GPU Developer’s Conference, NVIDIA’s CEO Jensen Huang took to the stage with a series of announcements.
openaire   +1 more source