Results 251 to 260 of about 26,389,358 (331)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Dual dimension assessment and green driven model for high quality industrial development level in Yangtze River Delta. [PDF]

Sci Rep
Shi X, Yang X, Liang W, Zheng L.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular profiling of signaling pathways involved in chicken ovarian follicle development by transcriptome sequencing. [PDF]

Front Vet Sci
Wadood AA, Bordbar F, Safdar M, Zhang X.
europepmc   +1 more source

Urbanization and Child Development: Investigating Socioeconomic, Structural, and Environmental Influences on Cognitive Development. [PDF]

Dev Sci
Sen U, Wangchuk, Dorji N, Nyström P, Hellberg J, Gredebäck G.   +5 more
europepmc   +1 more source

Medical students' perspectives on the role of OSPE and OSCE in the educational journey and contribution to career development: A cross-sectional study. [PDF]

Medicine (Baltimore)
Alrashed FA, Ahmad T, Alsubiheen AM, Alhammad SA, Aldaihan MM, Albishi AM, Hasan Z.   +6 more
europepmc   +1 more source

Development of the neurohypophysis: A major neuroendocrine interface. [PDF]

J Neuroendocrinol
Ramesh AR, Nedunchezhian N, Ali MH, Ali MH, Pęcherz S, Kowalewska N, Anbalagan S.   +6 more
europepmc   +1 more source

Review of early development in children with Down syndrome: family and clinician partnership. [PDF]

BMJ Paediatr Open
Kelly A, Morrison R, Matta N, Neville L.
europepmc   +1 more source