We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Insight into the genetic network governing long-stalked glandular trichome development in Nicotiana tabacum. [PDF]
Berhin A +7 more
europepmc +1 more source
Sakai Tutorials and User Guide [PDF]
Instructional Technology Development Program (ITDP)
core +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Regional differences, dynamic evolution, and driving factors of ecological resilience in China's urban agglomerations. [PDF]
Zhong X, Zheng R, Chen W, Lv L, Wei Z.
europepmc +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
A comprehensive strategy for pandemic preparedness with neutralizing monoclonal antibodies. [PDF]
Marx C +5 more
europepmc +1 more source
Temperature-dependent development, predation, and life table of <i>Sphaerophoria macrogaster</i> (Thomson) (Diptera: Syrphidae) feeding on <i>Myzus persicae</i> (Sulzer) (Homoptera: Aphididae). [PDF]
Fan J +8 more
europepmc +1 more source
Regeneration, investment, partnerships: a legacy [PDF]
East Midlands Development Agency, EMDA
core
Importance of skills development on labour market participation among workers aged 35 or older - a systematic review of prospective cohort studies. [PDF]
Seeberg KGV +5 more
europepmc +1 more source

