Results 71 to 80 of about 11,255,114 (312)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Validation of the development methodologies [PDF]
arXiv, 2014 This paper argues that modelling the development methodologies can improve the multi-agents systems software engineering. Such modelling allows applying methods, techniques and practices used in the software development to the methodologies themselves. The paper discusses then the advantages of the modelling of development methodologies. It describes a
arxiv
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
, 2009 This article situates and deconstructs the meanings associated with the term 'development' in the context of the developing world as they have been used by geographers. The arguments made highlight the deeply contested and fragmented terrain of development.
Willis, Katie, Kumar, M Satish
openaire +9 more sources
Challenges and issues in collaborative software developments [PDF]
arXiv, 2019 The software development process has evolved with respect to the problems in developing large and complex applications. There is a paradigm shift towards collaborative development, which necessitates the need to evaluate this approach. A number of tools are used for collaborative software development (CSD) including social media and web 2.0 features ...
arxiv
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Developing biobanks in developing countries.
Journal of global health, 2011 We call for the development of human biobanks in developing countries and describe several examples from low income countries which are already building their own biobanks. Developing human biobanks in developing countries requires strengthening of the research capacity to use the new technologies, as well as a shift in research investment priorities ...
Igor Rudan +2 more
openaire +3 more sources
The Development of Development Thinking [PDF]
The IDS Bulletin, 1977 Summary This article examines some of the main trends in the evolution of development thinking over the last 25 years or so, from three main perspectives: the nature of the political economies that constitute the object of development thought since 1950, and their international context; the nature of the economic thought prevailing when development ...
openaire +3 more sources
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source