Results 81 to 90 of about 47,379,055 (379)

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Key events in the history of sustainable development [PDF]

open access: yes, 2012
This document is a table which summaries the key events in the history of sustainable development, adapted from International Institute for Sustainable Development's sustainable development timeline.Publisher ...
Sustainable Development Commission
core  

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Consensus on endocrine management for children and adolescents with craniopharyngioma surgeries [PDF]

open access: yesJichu yixue yu linchuang
Craniopharyngioma is a rare benign tumor mainly occurs in the hypothalamus region of children. Patients may have a long survival after surgery. Tumors or operations may lead to hypothalamic syndrome, hypopituitarism, obesity, and a disturbed electrolytes
Growth and Development and Gonadal Diseases Committee of Chinese Aging Well Association
doaj   +1 more source

The Development of Development Thinking [PDF]

open access: yesThe IDS Bulletin, 1977
Summary This article examines some of the main trends in the evolution of development thinking over the last 25 years or so, from three main perspectives: the nature of the political economies that constitute the object of development thought since 1950, and their international context; the nature of the economic thought prevailing when development ...
openaire   +2 more sources

Supporting International Students In Your University Class [PDF]

open access: yes, 2018
University instructors have many options for supporting international students in ...
Bieszka, Terri
core   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Developing biobanks in developing countries.

open access: yesJournal of global health, 2011
We call for the development of human biobanks in developing countries and describe several examples from low income countries which are already building their own biobanks. Developing human biobanks in developing countries requires strengthening of the research capacity to use the new technologies, as well as a shift in research investment priorities ...
Igor Rudan   +2 more
openaire   +3 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Winds of change and the spatial Transformation of post-socialist cities [PDF]

open access: yesBaltic Worlds, 2013
The paper explores the new planning regimes and planning processes in post-socialist countries and their ability to influence the spatial transformation of cities.
Sasha Tsenkova, Professor of planning and international development
doaj  

Home - About - Disclaimer - Privacy