Results 91 to 100 of about 16,462,243 (264)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

External Assistance and its Effects on Eradicating Poverty [PDF]

open access: yesCSIE Working Papers Series, 2019
Poverty is a multidimensional socio- economic phenomenon. It entails more than the lack of income and productive resources to ensure sustainable livelihoods, its manifestations include hunger and malnutrition, limited access to education, health care and
Meri CAZACU, Rodica CRUDU
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

How does fair trade, as practised by Trade Aid and MINKA, contribute to the aspirations of Quechua producers in Peru? [PDF]

open access: yes, 2012
As part of a Master of Indigenous Studies from the University of Otago, Trade Aid staff member, Michelia Ward, conducted research throughout 2011 and 2012 on whether fair trade is able to contribute to the aspirations of indigenous producers.
Michelia Ward
core  

IDB Newsletter: Vol. 7, no. 4, October 1969

open access: yes, 1969
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

Cartographier les territorialités indigènes dans les Andes boliviennes : enjeux politiques, défis méthodologiques

open access: yesCybergeo, 2013
The analysis of maps and of their making uncovers territorial ideologies, as well as the sets of actors, political controversies and interests at stake. This article addresses the mapping of indigenous lands in Bolivia in the context of land reforms and ...
Irène Hirt, Louca Lerch
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Local Financial Development and the Aid-Growth Relationship [PDF]

open access: yes
With official development assistance (ODA) set to rise as countries strive to meet the Millennium Development Goals (MDGs), aid effectiveness remains an important area of development policy. An increasing number of studies support the notion that ODA can
Sayek, Selin, Nkusu, Mwanza
core  

IDB Newsletter: Vol. 6, no. 4, October 1968

open access: yes, 1968
IDB Newsletter is a monthly publication of the Inter-American Development that reports on the activities of the Inter-American Development Bank and appears in English and Spanish ...
Inter-American Development Bank
core   +1 more source

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