Results 191 to 200 of about 16,462,243 (264)

Analysis of bilateral development assistance for surgery in low- and middle-income countries: trends, challenges and opportunities. [PDF]

BMJ Glob Health
Fabry S, Hyman GY, Bulfeta NG, Jumbam DT, Varallo JE, Park KB.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Prioritizing Equity in Design and Implementation of Consumer-Facing Digital Resources to Support Engagement and Shared Decision-Making. [PDF]

J Med Internet Res
Smith J, Ayre J, Bonner C, Muscat D, Shepherd HL, Hussain E, Amani H, Tracy M, Weir KR, McFadden K, McCaffery KJ, Hersch J.   +11 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Shared decision making in pain care: a systematic review study protocol of decision aids. [PDF]

BMJ Open
Hess CW, McDonnell A, Sahaym O, Masood S, Davis A, Smyth H, Nguyen H, Wong C, Lipstein EA, Zisman-Ilani Y, Simons L.   +10 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Zwischen Öko-Kost und Designer Food : Ernährung im 21. Jahrhundert: Tagungsband 2. aid-Forum, Bonn

, 1999

core  

Development and acceptability of gist-based decision aids for prostate and breast cancer screening: a two-phase qualitative interview study in an online setting. [PDF]

BMJ Open
Nalavenkata S, Bergengren O, Lynch K, Emard N, Austria M, Martin S, Ogbennaya G, Dualeh K, Stevanovic K, Patel MI, Gonsky J, Vickers A, Fagerlin A, Hamilton JG, Hay JL, Carlsson S.   +15 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Financing fragility and pandemic preparedness in Central Asia: a policy review of aid volatility, donor dynamics, and health system resilience. [PDF]

Front Public Health
Rakhimov B, Choi JW, Kim KH.
europepmc   +1 more source