FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Iranian Journal of Public Health, 2013 Access to the right to the highest attainable level of health is a constitutional right that obliges governments and other players to take step to increase all individuals' chances of obtaining good health.
A Vosoogh Moghaddam +6 more
doaj
Correction to: Environmental impact assessment of a steel industry development plan using combined method involving Leopold matrix and RIAM. [PDF]
J Environ Health Sci Eng, 2022 Arani MH +5 more
europepmc +1 more source
Fly-by-light flight control system technology development plan [PDF]
The results of a four-month, phased effort to develop a Fly-by-Light Technology Development Plan are documented. The technical shortfalls for each phase were identified and a development plan to bridge the technical gap was developed.
Berwick, J. W. +4 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Permissive azotemia during acute kidney injury enables more rapid renal recovery and less renal fibrosis: a hypothesis and clinical development plan. [PDF]
Crit Care, 2022 Chawla LS.
europepmc +1 more source
Rubric for Assessing ICT Vision, Plan, Policies and Standards in Malaysian Higher Education [PDF]
, 2006 The paper proposes a rubric for assessing the ICT vision, plan, policies and standards in Malaysian higher education institutions. Based on a selection of twelve survey questionnaires and rubrics that are used to assess ICT implementation, the paper ...
Abdul Rahman, Azizah +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Qualitative analysis of Iranian sixth five-year economic, social, and cultural development plan from universal health coverage perspective. [PDF]
BMC Health Serv Res, 2021 Mahdavi M, Sajadi HS.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source