Results 81 to 90 of about 5,146,328 (297)

Further Education Funding Council : circular : 99/45 : ILT implementation plan [PDF]

open access: yes, 1999
"Outlines the implementation plan for information and learning technology (ILT) development within the sector from 1999 to 2002" -- front ...

core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Participation of women in grassroots development interventions: reflections on the experiences of development projects in Sudan [PDF]

open access: yes, 2009
This paper is based on an empirical study, conducted in 2005/06. It provides reflections on gender and development approaches employed in development projects in Sudan and identifies the challenges that development providers need to address when they ...
El-Gack, Nawal
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Disability support services strategic plan 2014 to 2018 [PDF]

open access: yes
The Ministry of Health’s Disability Support Services (DSS) group has developed a four-year Strategic Plan for 2014 to 2018. Summary The plan sets out the vision for Disability Support Services – that disabled people and their families are ...
Ministry of Health (New Zealand)
core  

Inner city housing study : interim report [PDF]

open access: yes, 1978
Report : vii, 78, [42] leaves : ill., maps. "August 18, 1978". Study team: Lloyd Axworthy, Project Director; Christine McKee, Project Manager; Jackie DeRoo, Sybil Frenette, Barbara Hanks. "In association with Frank W. Fedoruk"
Axworthy, Lloyd   +5 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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