Results 21 to 30 of about 968,002 (253)

Bilateral Radicular Dens Invaginatus in Mandibular First Premolars-Report of Two Rare Cases [PDF]

Journal of Clinical and Diagnostic Research, 2018
Dens invaginatus is a developmental dental anomaly which is clinically seen as a furrow on the palatal aspect of the tooth either limiting to the coronal pulp or extending to the radicular apex. It occurs most commonly in females affecting crowns of the
YM Karuna, Shailaja Datta, BS Suprabha, Arathi Rao, Ravikiran Ongole   +4 more
doaj   +1 more source

Unusual cause of dorsal compressive myelopathy - Double butterfly vertebra mimicking vertebral fracture

Journal of Spinal Surgery, 2022
Structural developmental anomalies affecting the vertebral column resulting in malformed vertebrae are numerous. It can arise secondary to errors of vertebral formation, fusion and/or segmentation and developmental variation.
Dig Vijay Singh Thakur, Nisarg Parmar, Rakesh Kumar Mishra, Bhagavatula Indira Devi   +3 more
doaj   +1 more source

Hyperplasia of the mandibular body: An anomaly in a developmental anomaly

Journal of Pharmacy and Bioallied Sciences, 2013
Hyperplasias of the mandible are usually seen in relation to the condyle or affecting one half of the mandible, such cases being described as hemimandibular hyperplasia or elongation.
Vaiyapuri Ravi, Saravanan Srinivasan, Mathew Jacob, Priya Kesavan, Rajathi Palani, Sekar Balakrishnan   +5 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Aqueductal developmental venous anomaly as an unusual cause of congenital hydrocephalus: a case report and review of the literature

Journal of Medical Case Reports, 2012
Introduction Aqueductal stenosis may be caused by a number of etiologies including congenital stenosis, tumor, inflammation, and, very rarely, vascular malformation.
Paulson David, Hwang Steven W, Whitehead William E, Curry Daniel J, Luerssen Thomas G, Jea Andrew   +5 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Developmental venous anomaly : MR and angiographic features

Journal of the Belgian Society of Radiology, 2014
Developmental venous anomaly (DVA) is probably the most common anomaly of the intracranial vasculature. DVAs consist of multiple, radially oriented dilated medullary veins that converge into a transcerebral vein.
M Faure, M Voormolen, T Van der Zijden, P M Parizel   +3 more
doaj   +1 more source

Prevalence and distribution of selected developmental dental anomalies in Taif, Saudi population

Journal of Public Health Research, 2021
Background: Developmental dental anomalies are seen as abnormalities in tooth size, shape, position, and structure due to multiple reasons during various stages of tooth development.
Theeb Saed Saad Aljuaid, Bhari Sharanesha Manjunatha, Holenarasipur Vasantakumar Amith, Rayan Ali Alshehri, Faisal Bandar Alharthi, Abdulrahman Mousa Kariri   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Prevalence and characteristics of talon cusps in Turkish population

Dental Research Journal, 2016
Background: Talon cusp is a rare dental anomaly characterized by a cusp-like projection, often including the palatal surface of the affected tooth. The aim of the present study was to investigate the prevalence and characteristics of talon cusps in a ...
Yeliz Guven, Yelda Kasimoglu, Elif Bahar Tuna, Koray Gencay, Oya Aktoren   +4 more
doaj   +1 more source