Results 251 to 260 of about 2,742,900 (350)

Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems. [PDF]

Semin Cell Dev Biol, 2023
McNamara HM, Ramm B, Toettcher JE.
europepmc   +1 more source

Human neonatal and infant airway epithelial biology: the new frontier for developmental immunology

, 2022
Gustavo Niño, María J. Gutiérrez, Carlos E. Rodríguez‐Martínez   +2 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Editorial: Developmental Biology and Regulation of Osteoclasts. [PDF]

Front Cell Dev Biol, 2021
Gabet Y, Neumann D, Levaot N, Elson A, Sims NA.   +4 more
europepmc   +1 more source

Illuminating developmental biology through photochemistry.

Nature Chemical Biology, 2017
Lukasz Kowalik, James K. Chen
semanticscholar   +1 more source

Evolution of the vertebrate jaw: comparative embryology and molecular developmental biology reveal the factors behind evolutionary novelty [PDF]

, 2004
Shigeru Kuratani
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Editorial: Network-based mathematical modeling in cell and developmental biology. [PDF]

Front Cell Dev Biol
Blinov ML, Mertins SD.
europepmc   +1 more source

Embryonic development of the annual killifish Austrofundulus limnaeus: An emerging model for ecological and evolutionary developmental biology research and instruction

Developmental Dynamics, 2017
J. Podrabsky, Claire L. Riggs, A. Romney, S. Woll, Josiah T. Wagner, Kristin M. Culpepper, Timothy G. Cleaver   +6 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source