Results 21 to 30 of about 2,742,900 (350)

A lncRNA perspective into (re)building the heart

open access: yesFrontiers in Cell and Developmental Biology, 2016
Our conception of the human genome, long focused on the 2% that codes for proteins, has profoundly changed since its first draft assembly in 2001. Since then, an unanticipatedly expansive functionality and convolution has been attributed to the majority ...
Stefan Frank   +4 more
doaj   +1 more source

X-Linked Huwe1 Is Essential for Oocyte Maturation and Preimplantation Embryo Development

open access: yesiScience, 2020
Summary: HUWE1 is a HECT-domain ubiquitin E3 ligase expressed in various tissues. Although HUWE1 is known to promote degradation of the tumor suppressor p53, given a growing list of its substrates, in vivo functions of HUWE1 remain elusive.
Alaa A. Eisa   +11 more
doaj   +1 more source

Protocol for isolation and ATAC-seq library construction of zebrafish red blood cells

open access: yesSTAR Protocols, 2022
Summary: Understanding chromatin dynamics in red blood cells (RBCs) is critical for exploring the differentiation process and homeostasis maintenance during erythropoiesis.
Yanyan Ding, Feng Liu
doaj   +1 more source

Acknowledgement to Reviewers of Journal of Developmental Biology in 2015

open access: yesJournal of Developmental Biology, 2016
The editors of Journal of Developmental Biology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Journal of Developmental Biology Editorial Office
doaj   +1 more source

Adamts18 modulates the development of the aortic arch and common carotid artery

open access: yesiScience, 2021
Summary: Members of a disintegrin and metalloproteinases with thrombospondin motif (ADAMTS) family have been implicated in various vascular diseases. However, their functional roles in early embryonic vascular development are unknown.
Shuai Ye   +10 more
doaj   +1 more source

An ATX-LPA6-Gα13-ROCK axis shapes and maintains caudal vein plexus in zebrafish

open access: yesiScience, 2021
Summary: Lysophosphatidic acid (LPA) is a potential regulator of vascular formation derived from blood. In this study, we utilized zebrafish as a model organism to monitor the blood vessel formation in detail.
Ryohei Okasato   +5 more
doaj   +1 more source

Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin [PDF]

open access: yes, 2018
Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the ...
Boxem, Mike   +12 more
core   +1 more source

The developmental cell biology of Trypanosoma brucei [PDF]

open access: yes, 2005
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
core   +2 more sources

Developmental Biology in Cyanobacteria

open access: yesLife, 2019
Filamentous, heterocyst-forming cyanobacteria are phototrophic multicellular organisms in which N2-fixing heterocysts and CO2-fixing vegetative cells exchange regulators and nutrients [...]
Antonia Herrero, Enrique Flores
doaj   +1 more source

Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation

open access: yesiScience, 2022
Summary: Activity-dependent calcium signals in developing muscle play a crucial role in neuromuscular junction (NMJ) formation. However, its downstream effectors and interactions with other regulators of pre- and postsynaptic differentiation are poorly ...
Mehmet Mahsum Kaplan   +1 more
doaj   +1 more source

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