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The developmental cell biology of Trypanosoma brucei [PDF]
Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
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Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo [PDF]
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030000) and the CAS-Novonordisk Foundation, as well as grants from the ‘1000 talents’ recruitment program, and a ‘Great-wall professorship’ from ...
Jin, Wanzhu+8 more
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Isolating and Quantifying the Role of Developmental Noise in Generating Phenotypic Variation [PDF]
Genotypic variation, environmental variation, and their interaction may produce variation in the developmental process and cause phenotypic differences among individuals. Developmental noise, which arises during development from stochasticity in cellular
Chiari, Ylenia+4 more
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The emerging models of human embryonic stem cell (hESC) self-organizing organoids provide a valuable in vitro platform for studying self-organizing processes that presumably mimic in vivo human developmental events. Here we report that through a chemical
Yijie Geng, Bradley Feng
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Genes Classical And Genes Developmental: The Different Uses Of The Gene In Evolutionary Synthesis [PDF]
Dobzhansky (1964) stated that “Nothing in biology makes sense except in the light of evolution,” and the function of the gene is no exception. The use of genes in population genetics and developmental genetics differs significantly.
Gilbert, Scott F.
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Evolutionary processes from the perspective of flowering time diversity. [PDF]
Although it is well appreciated that genetic studies of flowering time regulation have led to fundamental advances in the fields of molecular and developmental biology, the ways in which genetic studies of flowering time diversity have enriched the field
Blackman, Benjamin K, Gaudinier, Allison
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Developmental biology of the meninges [PDF]
SummaryThe meninges are membranous layers surrounding the central nervous system. In the head, the meninges lie between the brain and the skull, and interact closely with both during development. The cranial meninges originate from a mesenchymal sheath on the surface of the developing brain, called primary meninx, and undergo differentiation into three
Krishnakali Dasgupta, Juhee Jeong
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miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
Summary: Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling.
Liping Ouyang+12 more
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Philosophy of Developmental Biology
The history of developmental biology is interwoven with debates as to whether mechanistic explanations of development are possible or whether alternative explanatory principles or even vital forces need to be assumed. In particular, the demonstrated ability of embryonic cells to tune their developmental fate precisely to their relative position and the
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Progresses in developmental biology [PDF]
Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China E-mail: wujr@sibs.ac.cn Developmental biology is one of the most advanced areas in life science. JMCB has published several collections reporting the research findings that advance our understanding of the ...
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