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Social re-orientation and brain development: An expanded and updated view. [PDF]

, 2016
Social development has been the focus of a great deal of neuroscience based research over the past decade. In this review, we focus on providing a framework for understanding how changes in facets of social development may correspond with changes in ...
Guyer, Amanda E, Jarcho, Johanna M, Nelson, Eric E   +2 more
core   +8 more sources

Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function

Neurobiology of Disease, 2022
Hyperthyroidism has been identified as a risk factor for cognitive disorders. The hippocampus is a key brain region associated with cognitive function, among which excitatory synapse transmission plays an important role in the process of learning and ...
Wei Zhu, Fengming Wu, Jiong Li, Lianghui Meng, Wenjun Zhang, Huijie Zhang, Shuhan Cha, Jifeng Zhang, Guoqing Guo   +8 more
doaj   +1 more source

Social defeat drives hyperexcitation of the piriform cortex to induce learning and memory impairment but not mood-related disorders in mice

Translational Psychiatry, 2022
Clinical studies have shown that social defeat is an important cause of mood-related disorders, accompanied by learning and memory impairment in humans. The mechanism of mood-related disorders has been widely studied. However, the specific neural network
Hanjie Wang, Fang Li, Xuefeng Zheng, Lianghui Meng, Meiying Chen, Yuqing Hui, Yifei Li, Keman Xie, Jifeng Zhang, Guoqing Guo   +9 more
doaj   +1 more source

Infant selective attention to native and non-native audiovisual speech

Scientific Reports, 2022
The current study utilized eye-tracking to investigate the effects of intersensory redundancy and language on infant visual attention and detection of a change in prosody in audiovisual speech. Twelve-month-old monolingual English-learning infants viewed
Kelly C. Roth, Kenna R. H. Clayton, Greg D. Reynolds   +2 more
doaj   +1 more source

Phosphorylation of Spastin Promotes the Surface Delivery and Synaptic Function of AMPA Receptors

Frontiers in Cellular Neuroscience, 2022
Synaptic plasticity is essential for cognitive functions such as learning and memory. One of the mechanisms involved in synaptic plasticity is the dynamic delivery of AMPA receptors (AMPARs) in and out of synapses.
Li Chen, Hanjie Wang, Shuhan Cha, Jiong Li, Jiaqi Zhang, Jiaming Wu, Jiaming Wu, Guoqing Guo, Jifeng Zhang   +8 more
doaj   +1 more source

Structural Investigation of the Interaction Mechanism between Chlorogenic Acid and AMPA Receptor via In Silico Approaches

Molecules, 2022
Chlorogenic acid (CGA), an important metabolite in natural plant medicines such as honeysuckle and eucommia, has been shown to have potent antinociceptive effects. Nevertheless, the mechanism by which CGA relieves chronic pain remains unclear.
Wei Zhu, Fengming Wu, Jindie Hu, Wenjing Wang, Jifeng Zhang, Guoqing Guo   +5 more
doaj   +1 more source

Comprehensive Analysis of lncRNAs, miRNAs and mRNAs in Mouse Hippocampus With Hepatic Encephalopathy

Frontiers in Genetics, 2022
Hepatic encephalopathy (HE) often presents with varying degrees of cognitive impairment. However, the molecular mechanism of its cognitive impairment has not been fully elucidated.
Huijie Zhang, Huijie Zhang, Wenjun Zhang, Wenjun Zhang, Guangyin Yu, Fang Li, Yuqing Hui, Yuqing Hui, Shuhan Cha, Meiying Chen, Wei Zhu, Jifeng Zhang, Guoqing Guo, Xiaobing Gong, Xiaobing Gong   +14 more
doaj   +1 more source

Strategies for Targeting Neural Circuits: How to Manipulate Neurons Using Virus Vehicles

Frontiers in Neural Circuits, 2022
Viral strategies are the leading methods for mapping neural circuits. Viral vehicles combined with genetic tools provide the possibility to visualize entire functional neural networks and monitor and manipulate neural circuit functions by high-resolution
Yuqing Hui, Yuqing Hui, Xuefeng Zheng, Huijie Zhang, Huijie Zhang, Fang Li, Guangyin Yu, Jiong Li, Jifeng Zhang, Xiaobing Gong, Guoqing Guo   +10 more
doaj   +1 more source

Celsr3 is required for Purkinje cell maturation and regulates cerebellar postsynaptic plasticity

iScience, 2021
Summary: Atypical cadherin Celsr3 is critical for brain embryonic development, and its role in the postnatal cerebellum remains unknown. Using Celsr3-GFP mice, Celsr3 shows high expression in postnatal Purkinje cells (PCs). Mice with conditional knockout
Qinji Zhou, Jingwen Qin, Yaying Liang, Wei Zhang, Siyuan He, Fadel Tissir, Yibo Qu, Libing Zhou   +7 more
doaj   +1 more source

Neural correlates of deception in social contexts in normally developing children

Frontiers in Human Neuroscience, 2013
Deception is related to the ability to inhibit prepotent responses and to engage in mental tasks such as anticipating responses and inferring what another person knows, especially in social contexts. However, the neural correlates of deception processing,
Susumu eYokota, Susumu eYokota, Yasuyuki eTaki, Hiroshi eHashizume, Yuko eSassa, Benjamin eThyreau, Mari eTanaka, Ryuta eKawashima   +7 more
doaj   +1 more source