Results 161 to 170 of about 156,674 (242)
Combined Computational Systems Biology and Computational Neuroscience Approaches Help Develop of Future “Cognitive Developmental Robotics” [PDF]
, 2017 Faramarz Faghihi, Ahmed A. Moustafa
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Advanced Science, EarlyView.MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li +10 more
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Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
Advanced Science, EarlyView.The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
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Advanced Science, EarlyView.Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang +13 more
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Advanced Science, EarlyView.Bridging the gap between two crucial mechanisms of cooperation, namely direct reciprocity and partner choice, this study reveals the neurocognitive bases underlying how individuals prioritize reciprocal partner when receiving help from multiple benefactors with diverse intentions and reciprocal efficiency. The efficiency‐driven reciprocal decisions are
Rui Liao +5 more
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Advanced Science, EarlyView.Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
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Advanced Science, EarlyView.By integrating with machine learning (ML), hydrogel‐ and ionogel‐based soft sensors are gaining human brain‐like capabilities to perceive, learn, and predict. This review summarizes their advances, focusing on ML‐powered applications such as handwriting/gesture/object/motion/speech recognition, health monitoring, food detection, and beyond.
Wenqing He +8 more
wiley +1 more source
The Mindfulness Training in the Developmental Cognitive Neuroscience
, 2016 亚男 宋
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